SupplementDuel

CDP-Choline (Citicoline)

Nootropic

Choline + cytidine — both crossing the blood-brain barrier to support membrane integrity, dopamine, and acetylcholine. Strong stroke-recovery evidence.

focusmemorystroke-recoverydopamine
Typical dose
250–500 mg daily
Evidence
Moderate (some RCTs)
Onset time
Acute: 1–3 hours
Half-life
~70 hours
Forms
Capsule, Powder
Source
synthetic
Best taken with
with food
Best time of day
morning
Bioavailability
4/5
Safety rating
5/5
Price per serving
$0.90
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Find CDP-Choline (Citicoline)iHerb →

Vetted brands, third-party testing, ships worldwide.

Common uses

  • • Focus
  • • Memory
  • • Recovery from cognitive injury
  • • ADHD

Effect profile

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Common side effects

  • • Headache (rare)
  • • GI upset

Avoid if

  • • Bipolar (mania)

Drug interactions

  • • Levodopa

Related nootropic supplements

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Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.