SupplementDuel

L-Arginine

Amino Acid

Nitric oxide precursor — but most arginine is broken down in the gut. L-citrulline raises blood arginine more reliably for pumps.

pumpblood-flownitric-oxide
Typical dose
3–6 g daily (acute)
Evidence
Limited (small studies)
Onset time
Acute: 60 min
Half-life
~1 hour
Forms
Powder, Capsule
Source
microbial
Best taken with
empty stomach
Best time of day
pre-workout
Bioavailability
2/5
Safety rating
4/5
Price per serving
$0.35
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Find L-ArginineiHerb →

Vetted brands, third-party testing, ships worldwide.

Common uses

  • • Pump
  • • Erectile function
  • • Blood flow

Effect profile

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Common side effects

  • • GI upset
  • • Diarrhea (high doses)

Avoid if

  • • Recent heart attack
  • • Herpes flare-ups

Drug interactions

  • • Sildenafil, blood pressure meds

Related amino acid supplements

L-Arginine vs BCAAL-Arginine vs Essential Amino Acids (EAA)L-Arginine vs L-GlutamineL-Arginine vs L-Citrulline

Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.