Magnesium L-Threonate
SleepOnly magnesium form proven to cross the blood-brain barrier in animals. Marketed for cognitive aging and sleep, but premium-priced.
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Typical dose
1.5–2 g (≈144 mg elemental Mg)
Evidence
Limited (small studies)
Onset time
Cumulative: 4–12 weeks
Half-life
—
Forms
Capsule, Powder
Source
synthetic
Best taken with
evening
Best time of day
evening
Bioavailability
5/5
Safety rating
5/5
Price per serving
$1.10
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Common uses
- • Cognitive aging
- • Deep sleep
- • Memory
Effect profile
Strength
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Mood
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Sleep
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Immunity
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Recovery
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Longevity
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Common side effects
- • Drowsiness
- • Headache (rare)
Avoid if
- • Severe kidney disease
Drug interactions
- • Bisphosphonates
Related sleep supplements
Medical disclaimer
SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.