Valerian Root

Sleep

Traditional sedative herb that interacts with GABA receptors. Effects build over 2–4 weeks; less acute than melatonin.

sleepGABAanxietyherbal
Typical dose
300–600 mg extract
Evidence
Limited (small studies)
Onset time
Cumulative: 2–4 weeks
Half-life
—
Forms
Capsule, Liquid, Powder
Source
plant
Best taken with
30–60 min before bed
Best time of day
evening
Bioavailability
3/5
Safety rating
4/5
Price per serving
$0.20
Vegan / GF / 3rd-party
✓ / ✓ / ✓

Common uses

  • • Sleep
  • • Anxiety
  • • Restlessness

Effect profile

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Mood
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Common side effects

  • • Strong odor
  • • Morning grogginess
  • • Headache

Avoid if

  • • Liver disease
  • • Surgery (2 weeks before)

Drug interactions

  • • Sedatives
  • • Anesthetics
  • • Alcohol

Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.