SupplementDuel

MSM (Methylsulfonylmethane)

Joint & Recovery

Sulfur donor for connective tissue. Modest reductions in osteoarthritis pain and post-exercise muscle soreness.

jointsDOMSsulfurconnective-tissue
Typical dose
1500–3000 mg daily
Evidence
Moderate (some RCTs)
Onset time
Cumulative: 4–12 weeks
Half-life
—
Forms
Capsule, Powder, Tablet
Source
synthetic
Best taken with
with water
Best time of day
any
Bioavailability
4/5
Safety rating
5/5
Price per serving
$0.18
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Find MSM (Methylsulfonylmethane)iHerb →

Vetted brands, third-party testing, ships worldwide.

Common uses

  • • Joint pain
  • • Post-exercise soreness
  • • Skin / hair / nails

Effect profile

Strength
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Muscle
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Energy
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Mood
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Sleep
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Immunity
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Recovery
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Longevity
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Common side effects

  • • Mild GI upset
  • • Headache (rare)

Related joint & recovery supplements

MSM (Methylsulfonylmethane) vs Glucosamine SulfateMSM (Methylsulfonylmethane) vs Curcumin (with Piperine)

Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.