Resveratrol

Hormone

SIRT1 activator marketed for longevity. Human evidence is mixed; popular paired with NMN in anti-aging stacks.

SIRT1longevitypolyphenolNAD+
Typical dose
150–500 mg daily
Evidence
Limited (small studies)
Onset time
Cumulative: 4–12 weeks
Half-life
~9 hours
Forms
Capsule
Source
plant
Best taken with
fat-containing meal
Best time of day
morning
Bioavailability
2/5
Safety rating
4/5
Price per serving
$0.50
Vegan / GF / 3rd-party
✓ / ✓ / ✓

Common uses

  • Anti-aging
  • Cardiovascular
  • Polyphenol coverage

Effect profile

Strength
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Muscle
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Energy
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Focus
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Mood
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Sleep
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Immunity
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Recovery
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Longevity
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Common side effects

  • GI upset
  • Diarrhea (high doses)

Avoid if

  • Hormone-sensitive cancers (phytoestrogen)
  • Surgery (2 weeks before)

Drug interactions

  • CYP3A4 substrates
  • Anticoagulants

Related hormone supplements

Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.