Resveratrol
HormoneSIRT1 activator marketed for longevity. Human evidence is mixed; popular paired with NMN in anti-aging stacks.
SIRT1longevitypolyphenolNAD+
Typical dose
150–500 mg daily
Evidence
Limited (small studies)
Onset time
Cumulative: 4–12 weeks
Half-life
~9 hours
Forms
Capsule
Source
plant
Best taken with
fat-containing meal
Best time of day
morning
Bioavailability
2/5
Safety rating
4/5
Price per serving
$0.50
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Common uses
- • Anti-aging
- • Cardiovascular
- • Polyphenol coverage
Effect profile
Strength
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Muscle
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Energy
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Focus
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Mood
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Sleep
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Immunity
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Recovery
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Longevity
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Common side effects
- • GI upset
- • Diarrhea (high doses)
Avoid if
- • Hormone-sensitive cancers (phytoestrogen)
- • Surgery (2 weeks before)
Drug interactions
- • CYP3A4 substrates
- • Anticoagulants
Related hormone supplements
Medical disclaimer
SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.