SupplementDuel

Vitamin K2 (MK-7)

Vitamin

Activates osteocalcin and matrix-Gla protein to direct calcium into bones rather than arteries. Most evidence comes from the 3-year Rotterdam study.

bonearterial-healthcalcium-regulationlongevity
Typical dose
100–200 mcg daily
Evidence
Moderate (some RCTs)
Onset time
Cumulative: 4–12 weeks
Half-life
~72 hours
Forms
Softgel, Capsule
Source
microbial
Best taken with
fat-containing meal
Best time of day
any
Bioavailability
4/5
Safety rating
4/5
Price per serving
$0.18
Vegan / GF / 3rd-party
✓ / ✓ / ✓
Find Vitamin K2 (MK-7)iHerb →

Vetted brands, third-party testing, ships worldwide.

Common uses

  • • Bone density
  • • Arterial health
  • • Calcium routing

Effect profile

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Common side effects

  • • Generally none

Avoid if

  • • Warfarin therapy

Drug interactions

  • • Warfarin (major)
  • • Other anticoagulants

Related vitamin supplements

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Medical disclaimer

SupplementDuel is for educational purposes only and is not medical advice. Consult a physician before starting, stopping, or combining supplements.